SCHEMBL20630673

SCHEMBL20630673

CCCCC[C@@H](N)CCC[C@H](CCCCC)COC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 5/20 0.44
S1PR1 P21453 5/20 0.44
S1PR3 Q99500 5/20 0.44
S1PR4 O95977 4/20 0.44
TSHR P16473 2/20 0.42
CYP3A4 P08684 2/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA2 P00918 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.38
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
LAP3 P28838 1/20 0.37
GRIK1 P39086 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20629845 0.95 CYP3A4 (0.47) S1PR2S1PR1S1PR3S1PR4TSHR
SCHEMBL19025418 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL17676317 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL19025446 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL4582699 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL30522611 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL18723036 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL18856287 0.88 PRSS1 (0.51) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL3859828 0.86 TSHR (0.47) TSHRCYP3A4ATMTDP1PRSS1
SCHEMBL7103472 0.86 ALDH1A1 (0.47) S1PR2S1PR1S1PR3S1PR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3424941-A1 PRODUCTION METHOD FOR NONCYCLIC PEPTIDE-NUCLEIC ACID COMPLEX HAVING, AT N-TERMINAL, AMINO ACID WITH THIOL GROUP NEAR AMINO GROUP, LIBRARY THEREOF, AND CYCLIC PEPTIDE-NUCLEIC ACID COMPLEX LIBRARY DERIVED FROM SAME Chugai Seiyaku Kabushiki Kaisha (JP) 2019-01-09 EP disclosed