Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630785 | 1.00 | POLH (0.66) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL20630951 | 0.87 | POLH (0.67) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL20630788 | 0.84 | POLH (0.70) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL20630211 | 0.83 | POLH (0.67) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL27142114 | 0.83 | POLH (0.78) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL30728553 | 0.83 | POLH (0.78) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL30728551 | 0.80 | POLH (0.77) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL27140476 | 0.80 | POLH (0.80) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL30728552 | 0.80 | POLH (0.80) | POLHGAAKDM4EPOLBMAPT | |
| SCHEMBL25304942 | 0.80 | POLH (1.00) | POLHGAAKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |