Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633090 | 0.85 | TLR8 (0.35) | TLR8TRPV3HDAC4 | |
| SCHEMBL20631622 | 0.83 | MEN1 (0.36) | TLR8HDAC4MEF2D | |
| SCHEMBL20632107 | 0.83 | TLR8 (0.35) | TLR8CNR1HDAC4MEF2D | |
| SCHEMBL20632264 | 0.83 | TLR8 (0.40) | TLR8HDAC4MEF2DKDM1A | |
| SCHEMBL20632126 | 0.83 | TLR8 (0.34) | TLR8HDAC4MEF2D | |
| SCHEMBL20632633 | 0.83 | TLR8 (0.34) | TLR8HDAC4MEF2D | |
| SCHEMBL20632765 | 0.83 | TLR8 (0.34) | TLR8CNR1 | |
| SCHEMBL20632368 | 0.81 | TLR8 (0.33) | TLR8 | |
| SCHEMBL20632487 | 0.80 | TLR8 (0.44) | TLR8TRPV3CNR1CTSSCTSK | |
| SCHEMBL20632955 | 0.79 | TLR8 (0.41) | TLR8CTSSCTSKKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |