Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633402 | 0.83 | CREBBP (0.32) | GRIN1GRIN2B | |
| SCHEMBL20632810 | 0.83 | PHGDH (0.38) | GRIN1GRIN2B | |
| SCHEMBL20632375 | 0.82 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL20631424 | 0.82 | GRIN1 (0.34) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL20632431 | 0.82 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL20632750 | 0.82 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL20633137 | 0.81 | GRIN1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL20632238 | 0.81 | GRIN1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL20632711 | 0.79 | KDM1A (0.34) | TDP1GRIN1GRIN2B | |
| SCHEMBL20632939 | 0.79 | GRIN1 (0.41) | TDP1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |