Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20632940 | 0.94 | TEK (0.33) | TGFBR1CCNA2CDK2CCNA1ROCK2 | |
| SCHEMBL20632238 | 0.92 | GRIN1 (0.34) | GRIN1GRIN2BTRPV1KCNH2 | |
| SCHEMBL20631681 | 0.87 | BRAF (0.32) | — | |
| SCHEMBL20632750 | 0.85 | GRIN1 (0.37) | GRIN1GRIN2BCCNA2CDK2CCNA1 | |
| SCHEMBL20631471 | 0.84 | BCL6 (0.33) | CCNA2CDK2 | |
| SCHEMBL20631532 | 0.83 | HTR2C (0.40) | GRIN1GRIN2BCCNA2CDK2CCNA1 | |
| SCHEMBL20633043 | 0.83 | TRPV3 (0.36) | GRIN1GRIN2BTGFBR1CCNA2CDK2 | |
| SCHEMBL19670295 | 0.83 | HTR2C (0.39) | TRPV1 | |
| SCHEMBL20632313 | 0.83 | PHGDH (0.33) | CCNA2CDK2CCNA1 | |
| SCHEMBL20633129 | 0.81 | MEN1 (0.32) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |