SCHEMBL20633657

SCHEMBL20633657

c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccc(-c8ccccc8)cc6n7-c6ccccc6)ccc54)c3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TSPO P30536 3/20 0.41
KMT2A Q03164 3/20 0.39
IL1R1 P14778 1/20 0.39
HDAC4 P56524 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 1/20 0.38
FAAH O00519 1/20 0.38
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.38
MGLL Q99685 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
AVPR1A P37288 1/20 0.37
PTGER4 P35408 1/20 0.37
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19762206 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL17178957 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL16727287 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL22198451 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL23370378 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL23604111 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL20633776 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL23370471 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL20632554 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL20391675 1.00 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019233904-A1 ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 L3MBTL1 3718/4885ATM 4360/4885KDM4E 3376/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 L3MBTL1 3258/4885ATM 4632/4885KDM4E 3745/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 L3MBTL1 3258/4885ATM 4632/4885KDM4E 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.