Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20760068 | 0.90 | CA2 (0.39) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL18898543 | 0.86 | TDP1 (0.39) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL18386943 | 0.79 | CA2 (0.46) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL19629980 | 0.79 | CA2 (0.41) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL21078459 | 0.77 | CA2 (0.41) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL22203322 | 0.76 | CA2 (0.41) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL4071822 | 0.72 | SMN1; SMN2 (0.68) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL4638239 | 0.71 | CA2 (0.59) | CA2SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL21585329 | 0.71 | CA2 (0.37) | CA2SMN1; SMN2POLBCA1CA9 | |
| SCHEMBL18456642 | 0.70 | CA2 (0.42) | CA2SMN1; SMN2DHFRTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228788-A1 | 2-BROMO-6-ALKOXYPHENYL-SUBSTITUTED PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019007793-A1 | NOVEL ISOTHIAZOLO-BASED BICYCLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-10 | — | — | WO | disclosed |