SCHEMBL20634845

SCHEMBL20634845

CCCC1CCC(c2ccc(OC)c(-c3cc(C4CCC(CC)CC4)ccc3OC)c2)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.45
ALDH1A1 P00352 2/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 1/20 0.42
CCNT1 O60563 1/20 0.38
CDK9 P50750 1/20 0.38
HTR1A P08908 2/20 0.38
HTR1D P28221 2/20 0.38
HTR1B P28222 2/20 0.38
HTR2A P28223 2/20 0.38
HTR1E P28566 2/20 0.38
HTR7 P34969 2/20 0.38
HTR2B P41595 2/20 0.38
HTR3A P46098 2/20 0.38
HTR5A P47898 2/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24426577 0.85 PDE4A (0.39) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL8571926 0.82 CYP2C9 (0.40) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11035523 0.82 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11035526 0.82 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11035520 0.82 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL14747863 0.80 CYP2C9 (0.47) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11195056 0.80 CYP2C9 (0.63) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11195061 0.80 CYP2C9 (0.63) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL8568658 0.79 CARM1 (0.36) CCNT1CDK9HTR1AHTR1DHTR1B
SCHEMBL8730868 0.77 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907864-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THIS COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2019-01-09 EP disclosed