SCHEMBL8730868

SCHEMBL8730868

CCCCCc1cc([C@H]2CC[C@H](CCC)CC2)ccc1OC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.42
SLC6A2 P23975 5/20 0.41
SLC6A4 P31645 5/20 0.41
SLC6A3 Q01959 5/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
SPHK1 Q9NYA1 2/20 0.40
HTT P42858 1/20 0.40
HTR2A P28223 2/20 0.39
ALOX5 P09917 2/20 0.39
PTGS2 P35354 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8727009 1.00 CYP2C9 (0.42) CYP2C9SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL10523484 0.96 CYP2C9 (0.40) CYP2C9SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL8728053 0.84 ALOX5 (0.38) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8728051 0.84 ALOX5 (0.38) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8728057 0.84 ALOX5 (0.38) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8727521 0.84 SPHK1 (0.40) ALDH1A1MAPTSPHK1HTT
SCHEMBL8727006 0.84 HTR2A (0.44) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8727598 0.82 SPHK1 (0.39) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8727605 0.82 SPHK1 (0.39) SLC6A2SLC6A4SLC6A3SPHK1HTR2A
SCHEMBL8727917 0.82 SPHK1 (0.41) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed