SCHEMBL20635532

SCHEMBL20635532

COC(=O)C(Cc1ccc(OS(=O)(=O)Oc2ccccc2O[C@@H]2O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 9/20 0.42
▸ CA2 P00918 9/20 0.42
▸ CA9 Q16790 9/20 0.42
▸ CA1 P00915 8/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20634547 1.00 CA12 (0.42) CA12CA2CA9CA1
SCHEMBL20634016 0.94 CA12 (0.40) CA12CA2CA9CA1
SCHEMBL24109366 0.90 CA12 (0.38) CA12CA2CA9CA1
SCHEMBL22193988 0.88 CA12 (0.38) CA12CA2CA9CA1
SCHEMBL24120437 0.88 CA12 (0.38) CA12CA2CA9CA1
SCHEMBL22193919 0.88 CA12 (0.38) CA12CA2CA9CA1
SCHEMBL20635300 0.87 KLK5 (0.37) —
SCHEMBL20634546 0.84 SLC5A1 (0.35) CA12CA2CA9CA1
SCHEMBL20634584 0.84 CA12 (0.49) CA12CA2CA9CA1
SCHEMBL22194038 0.83 LMNA (0.36) CA12CA2CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 — — US disclosed
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 — — US disclosed
US-20210388017-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KP) 2021-12-16 — — US disclosed
WO-2019008441-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2019-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210388017-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF VIP, ANTXR2, TNFRSF9 CA12 60/4885CA2 225/4885CA9 247/4885
US-11753431-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 CA12 60/4885CA2 225/4885CA9 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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