Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629339 | 0.88 | HDAC2 (0.49) | — | |
| SCHEMBL20605349 | 0.85 | HDAC6 (0.44) | — | |
| SCHEMBL20629473 | 0.79 | HDAC2 (0.49) | — | |
| SCHEMBL20629509 | 0.78 | HDAC2 (0.46) | — | |
| SCHEMBL20628946 | 0.76 | HDAC6 (0.41) | — | |
| SCHEMBL20628955 | 0.75 | HDAC6 (0.47) | — | |
| Hydrochloric Acid SCHEMBL20605300 | 0.75 | HDAC6 (0.46) | — | |
| SCHEMBL17520651 | 0.69 | HDAC6 (0.64) | — | |
| SCHEMBL17520600 | 0.69 | HDAC6 (0.64) | — | |
| SCHEMBL19139014 | 0.68 | HDAC6 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019007836-A1 | NOVEL HDAC6 INHIBITORS, WITH IMPROVED SOLUBILITY AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2019-01-10 | — | — | WO | disclosed |