Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635927 | 0.88 | NPC1 (0.34) | NPC1RAB9AKDM4ELMNACA12 | |
| SCHEMBL17697064 | 0.84 | PTGS2 (0.35) | NPC1RAB9AKDM4ELMNACA12 | |
| SCHEMBL15868327 | 0.83 | NPC1 (0.40) | NPC1RAB9AKDM4ELMNACA12 | |
| SCHEMBL20635348 | 0.83 | NPC1 (0.32) | NPC1RAB9AKDM4ELMNACA12 | |
| SCHEMBL20635343 | 0.82 | NPC1 (0.31) | NPC1RAB9ACARM1 | |
| SCHEMBL24286095 | 0.81 | ALOX5AP (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL20628411 | 0.80 | POLB (0.32) | NPC1RAB9A | |
| SCHEMBL29431625 | 0.79 | HTR2B (0.38) | NPC1RAB9AKDM4ECA12CA9 | |
| SCHEMBL14684635 | 0.79 | HTR2B (0.38) | NPC1RAB9AKDM4ECA12CA9 | |
| SCHEMBL17331330 | 0.78 | MAPT (0.43) | NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008115-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-10 | — | — | WO | disclosed |