Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 3/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092591 | 0.92 | UCHL1 (0.34) | UCHL1LIPESOS1MYCMAPT | |
| SCHEMBL29570855 | 0.87 | UCHL1 (0.34) | UCHL1LIPESOS1MYCMAPT | |
| SCHEMBL17201213 | 0.86 | UCHL1 (0.33) | UCHL1LIPESOS1MYCMAPT | |
| SCHEMBL17201112 | 0.84 | UCHL1 (0.34) | UCHL1MYCMAPTKDM4EALDH1A1 | |
| SCHEMBL30153179 | 0.83 | UCHL1 (0.36) | UCHL1LIPEMYCMAPTJAK2 | |
| SCHEMBL16034782 | 0.83 | UCHL1 (0.36) | UCHL1LIPEMYCMAPTJAK2 | |
| SCHEMBL20477784 | 0.83 | KDM4E (0.39) | UCHL1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL20636622 | 0.83 | KDM4E (0.37) | UCHL1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL18107886 | 0.82 | CA12 (0.37) | UCHL1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL31394282 | 0.81 | KDM4E (0.35) | UCHL1LIPESOS1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428150-B1 | AROMATIC RING COMPOUND HAVING A CHOLINERGIC MUSCARINE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATOR ACTIVITY | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-12 | — | — | EP | disclosed |
| US-10548877-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-04 | — | — | US | disclosed |
| US-20190083467-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-03-21 | — | — | US | disclosed |
| EP-3428150-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190083467-A1 | AROMATIC RING COMPOUND | CHRM1, CHRM2, CHRM4 | UCHL1 1506/4885LIPE 4086/4885SOS1 1464/4885 |
| US-10548877-B2 | Aromatic ring compound | CHRM1, CHRM2, CHRM4 | UCHL1 1506/4885LIPE 4086/4885SOS1 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.