Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 19/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20636663 | 0.89 | CHRM1 (0.51) | CHRM1PDE2APDE11A | |
| SCHEMBL20636628 | 0.86 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL20636617 | 0.85 | CHRM1 (0.59) | CHRM1PDE2APDE11A | |
| SCHEMBL19353595 | 0.85 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL20651971 | 0.85 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL20636631 | 0.82 | CHRM1 (0.48) | CHRM1 | |
| SCHEMBL20652295 | 0.81 | CHRM1 (0.44) | CHRM1PDE2APDE11A | |
| SCHEMBL23698933 | 0.80 | CHRM1 (0.50) | CHRM1PDE2APDE11A | |
| SCHEMBL20636673 | 0.80 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL20636655 | 0.79 | CHRM1 (0.53) | CHRM1PDE2APDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428150-B1 | AROMATIC RING COMPOUND HAVING A CHOLINERGIC MUSCARINE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATOR ACTIVITY | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-12 | — | — | EP | disclosed |
| US-10548877-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-04 | — | — | US | disclosed |
| US-20190083467-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-03-21 | — | — | US | disclosed |
| EP-3428150-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190083467-A1 | AROMATIC RING COMPOUND | CHRM1, CHRM2, CHRM4 | CHRM1 1/4885PDE2A 1552/4885PDE11A 2099/4885 |
| US-10548877-B2 | Aromatic ring compound | CHRM1, CHRM2, CHRM4 | CHRM1 1/4885PDE2A 1552/4885PDE11A 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.