Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640394 | 1.00 | OPRM1 (0.54) | OPRM1OPRL1 | |
| SCHEMBL20640395 | 1.00 | OPRM1 (0.54) | OPRM1OPRL1 | |
| SCHEMBL20647590 | 0.70 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL20640178 | 0.70 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL23316671 | 0.68 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL20647537 | 0.66 | OPRM1 (0.65) | OPRM1OPRL1 | |
| SCHEMBL20864110 | 0.65 | OPRM1 (0.45) | OPRM1OPRL1 | |
| SCHEMBL20640258 | 0.63 | OPRM1 (0.62) | OPRM1OPRL1 | |
| SCHEMBL20647517 | 0.63 | OPRM1 (0.62) | OPRM1OPRL1 | |
| SCHEMBL23316836 | 0.60 | KDM1A (0.46) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652157-A1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | Grünenthal GmbH (DE) | 2020-05-20 | — | — | EP | disclosed |
| WO-2019012037-A1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | Grünenthal GmbH (DE) | 2019-01-17 | — | — | WO | disclosed |