Malonyl-Coenzyme A

Malonyl-Coenzyme A

SCHEMBL20641455

C.CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCSC(=O)CC(=O)O

nearest known ligand 0.99

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.87
▸ CHAT P28329 2/20 0.83
▸ EP300 Q09472 3/20 0.82
▸ KAT5 Q92993 2/20 0.82
▸ AURKA O14965 2/20 0.82
▸ KAT2B Q92831 1/20 0.82
▸ CREBBP Q92793 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonyl-Coenzyme A SCHEMBL28164738 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL30109215 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL30109292 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL14593552 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL13461519 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL2125762 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL6450 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL20502471 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL27930376 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Malonyl-Coenzyme A SCHEMBL27943558 0.99 NAA50 (0.88) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781148-B2 Biological methods for preparing terpenes RADICI CHIMICA S.P.A. (IT) 2023-10-10 — — US disclosed
US-11174488-B2 Biological methods for modifying cellular carbon flux RADICI CHIMICA S.P.A. (IT) 2021-11-16 — — US disclosed
US-20210079408-A1 BIOLOGICAL METHODS FOR PREPARING TERPENES RADICI CHIMICA S.P.A. (IT) 2021-03-18 — — US disclosed
EP-3652192-A1 BIOLOGICAL METHODS FOR PREPARING TERPENES Radici Chimica S.p.A. (IT) 2020-05-20 — — EP disclosed
EP-3652300-A1 BIOLOGICAL METHODS FOR MODIFYING CELLULAR CARBON FLUX Radici Chimica S.p.A. (IT) 2020-05-20 — — EP disclosed
US-20200131522-A1 BIOLOGICAL METHODS FOR MODIFYING CELLULAR CARBON FLUX RADICI CHIMICA S.P.A. (IT) 2020-04-30 — — US disclosed
WO-2019014310-A1 BIOLOGICAL METHODS FOR PREPARING TERPENES VERDEZYNE (ABC), LLC (US) 2019-01-17 — — WO disclosed
WO-2019014309-A1 BIOLOGICAL METHODS FOR MODIFYING CELLULAR CARBON FLUX VERDEZYNE (ABC), LLC (US) 2019-01-17 — — WO disclosed
Send feedback