Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 5/20 | 0.58 |
| ▸ | NPY1R | P25929 | 4/20 | 0.58 |
| ▸ | NPY2R | P49146 | 4/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.51 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064604 | 1.00 | NPY4R (0.58) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL30973663 | 0.95 | OPRD1 (0.55) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL30973665 | 0.95 | OPRD1 (0.55) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL3649802 | 0.95 | NPY4R (0.67) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL3649800 | 0.95 | NPY4R (0.67) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL30973669 | 0.94 | OPRD1 (0.54) | NPY4RNPY1RNPY2ROPRD1OPRM1 | |
| SCHEMBL29576811 | 0.94 | NPY4R (0.59) | NPY4RNPY1RNPY2ROPRD1MMP2 | |
| SCHEMBL29577087 | 0.94 | NPY4R (0.59) | NPY4RNPY1RNPY2ROPRD1MMP2 | |
| SCHEMBL30851358 | 0.92 | NPY4R (0.63) | NPY4RNPY1RNPY2RMMP2NPY5R | |
| SCHEMBL30973680 | 0.91 | GNPAT (0.59) | OPRD1OPRM1MMP2GNPATSSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| US-8629299-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-01-14 | — | — | US | disclosed |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| US-8445721-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
| US-8148575-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | HAMMERSMITH IMANET LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
| EP-2010227-A2 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | Hammersmith Imanet Limited (GB) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122488-A2 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | PSMA5, MPI, PSMA3 | NPY4R 2191/4885NPY1R 2272/4885NPY2R 2682/4885 |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | NPY4R 2191/4885NPY1R 2272/4885NPY2R 2682/4885 |
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | PSMA5, MPI, PSMA3 | NPY4R 2191/4885NPY1R 2272/4885NPY2R 2682/4885 |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | NPY4R 2191/4885NPY1R 2272/4885NPY2R 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.