Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820642 | 0.78 | HSD17B10 (0.43) | PNPTK1KDM4EALDH1A1LMNA | |
| SCHEMBL12820579 | 0.75 | HTT (0.46) | PNPKDM4EALDH1A1LMNAGLA | |
| SCHEMBL12820575 | 0.72 | MEN1 (0.45) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL23920795 | 0.71 | PNP (0.52) | PNPTK1HSD17B10HPRT1 | |
| SCHEMBL12820769 | 0.69 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL10007309 | 0.67 | KDM4E (0.49) | PNPKDM4EALDH1A1LMNAGLA | |
| SCHEMBL23920942 | 0.67 | PNP (0.50) | PNPTK1HSD17B10HPRT1 | |
| SCHEMBL12820638 | 0.66 | SCN9A (0.56) | ALDH1A1 | |
| SCHEMBL12958939 | 0.65 | DAO (0.50) | PNPKDM4EALDH1A1LMNAGLA | |
| SCHEMBL12820639 | 0.64 | MAOB (0.52) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041942-A9 | NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |