Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212987 | 0.77 | TRIM24 (0.36) | ALDH1A1 | |
| SCHEMBL7975876 | 0.74 | KDM1A (0.42) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL12208421 | 0.73 | MEN1 (0.42) | SLC6A2HPGDSLC6A3LMNAL3MBTL1 | |
| SCHEMBL4605961 | 0.70 | SLC6A2 (0.51) | SLC6A2RAB9AALDH1A1HPGDEPHX1 | |
| SCHEMBL4605964 | 0.70 | SLC6A2 (0.51) | SLC6A2RAB9AALDH1A1HPGDEPHX1 | |
| SCHEMBL1644777 | 0.70 | SLC6A2 (0.48) | SLC6A2RAB9ANPY1RNPY2RNPY4R | |
| SCHEMBL4605965 | 0.70 | SLC6A2 (0.51) | SLC6A2RAB9AALDH1A1HPGDEPHX1 | |
| SCHEMBL5146562 | 0.70 | SLC6A2 (0.46) | SLC6A2RAB9AALDH1A1HPGDEPHX1 | |
| SCHEMBL21768000 | 0.70 | PDE4B (0.47) | NPC1 | |
| Acrolein SCHEMBL6271087 | 0.69 | MEN1 (0.39) | SLC6A2HPGDSLC6A4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190016742-A1 | Complexes | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016742-A1 | Complexes | C5, C1S, C9 | SLC6A2 3129/4885RAB9A 2806/4885NPC1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.