Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240506 | 0.84 | KMT2A (0.42) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10028025 | 0.83 | RAB9A (0.57) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL12157064 | 0.79 | KMT2A (0.43) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL24297010 | 0.79 | ELANE (0.41) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17277530 | 0.79 | HDAC3 (0.54) | KMT2AMEN1SMN1; SMN2RAB9AGAA | |
| SCHEMBL27305897 | 0.78 | ELANE (0.52) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL27113593 | 0.78 | KLKB1 (0.47) | RAB9AGAAHPGDLMNANPC1 | |
| SCHEMBL13596295 | 0.78 | MEN1 (0.56) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL18792766 | 0.77 | ELANE (0.46) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL23420957 | 0.76 | KMT2A (0.43) | KMT2AMEN1L3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905770-B2 | Topical delivery of therapeutic agents using cell-penetrating peptides for the treatment of age-related macular degeneration and other eye diseases | MACREGEN, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20190015521-A1 | TOPICAL DELIVERY OF THERAPEUTIC AGENTS USING CELL-PENETRATING PEPTIDES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER EYE DISEASES | MACREGEN, INC. | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190015521-A1 | TOPICAL DELIVERY OF THERAPEUTIC AGENTS USING CELL-PENETRATING PEPTIDES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER EYE DISEASES | NPC1L1, STARD3, CETP | KMT2A 3881/4885MEN1 3419/4885L3MBTL1 2414/4885 |
| US-10905770-B2 | Topical delivery of therapeutic agents using cell-penetrating peptides for the treatment of age-related macular degeneration and other eye diseases | NPC1L1, STARD3, CETP | KMT2A 3881/4885MEN1 3419/4885L3MBTL1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.