Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CDK4 | P11802 | 3/20 | 0.34 |
| ▸ | CCND3 | P30281 | 3/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649298 | 0.93 | BTK (0.33) | CCNA2CDK2CDK4CCND3CDK6 | |
| SCHEMBL20649191 | 0.87 | CDK4 (0.31) | CCNA2CDK2CDK4CCND3CDK6 | |
| SCHEMBL20648930 | 0.87 | CDK4 (0.30) | CCNA2CDK2CDK4CCND3CDK6 | |
| SCHEMBL20649343 | 0.85 | — | — | |
| SCHEMBL20649094 | 0.85 | — | — | |
| SCHEMBL20649260 | 0.83 | — | — | |
| SCHEMBL20649255 | 0.83 | CDK2 (0.33) | CCNA2CDK2CDK4CCND3CDK6 | |
| SCHEMBL20649393 | 0.83 | — | — | |
| SCHEMBL20649087 | 0.82 | CCNA2 (0.33) | CCNA2CDK2CDK4CCND3CDK6 | |
| SCHEMBL20649152 | 0.78 | CDK4 (0.32) | CCNA2CDK2CDK4CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |