Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649024 | 0.90 | RIPK1 (0.31) | — | |
| SCHEMBL20649330 | 0.86 | CDK4 (0.32) | CDK4CCNA2CDK2CCND3 | |
| SCHEMBL20649255 | 0.86 | CDK2 (0.33) | CDK4CCNA2CDK2CCND3CDK6 | |
| SCHEMBL20648930 | 0.84 | CDK4 (0.30) | CDK4CCNA2CDK2CCND3CDK6 | |
| SCHEMBL20649033 | 0.83 | PDGFRB (0.30) | — | |
| SCHEMBL20649087 | 0.83 | CCNA2 (0.33) | CDK4CCNA2CDK2CCND3CDK6 | |
| SCHEMBL20649191 | 0.81 | CDK4 (0.31) | CDK4CCNA2CDK2CCND3CDK6 | |
| SCHEMBL20649197 | 0.81 | PDGFRB (0.41) | CDK4CCNA2CDK2CCND3CDK6 | |
| SCHEMBL20648927 | 0.81 | ACVR2A (0.40) | — | |
| SCHEMBL30183097 | 0.81 | ACVR2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |