Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 9/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648883 | 1.00 | MAP3K5 (0.36) | MAP3K5TP53MAPTLMNANPC1 | |
| SCHEMBL20648885 | 0.99 | MAP3K5 (0.36) | MAP3K5TP53MAPTLMNANPC1 | |
| SCHEMBL20648879 | 0.99 | MAP3K5 (0.36) | MAP3K5TP53MAPTLMNANPC1 | |
| SCHEMBL20648880 | 0.90 | TP53 (0.34) | MAP3K5TP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL20648886 | 0.90 | TP53 (0.34) | MAP3K5TP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL20648878 | 0.89 | TP53 (0.34) | MAP3K5TP53MAPTLMNASMN1; SMN2 | |
| SCHEMBL20648776 | 0.86 | MAP3K5 (0.39) | MAP3K5MAPTLMNANPC1RAB9A | |
| SCHEMBL20649215 | 0.83 | MAP3K5 (0.46) | MAP3K5MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20648931 | 0.82 | CA2 (0.34) | LMNANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL20648656 | 0.82 | NPC1 (0.39) | MAP3K5LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |