Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | AURKA | O14965 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649227 | 0.93 | DCPS (0.38) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| SCHEMBL30183190 | 0.92 | ACKR3 (0.36) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| SCHEMBL20649082 | 0.92 | ACKR3 (0.36) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| Hydrochloric Acid SCHEMBL30183135 | 0.92 | DCPS (0.38) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| Hydrochloric Acid SCHEMBL21875647 | 0.92 | DCPS (0.38) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| SCHEMBL30183727 | 0.91 | DCPS (0.37) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| SCHEMBL20649269 | 0.91 | DCPS (0.37) | ACKR3DCPSCSNK2A1CDK2AURKA | |
| SCHEMBL20649081 | 0.89 | F2 (0.43) | CSNK2A1F2F10MAOBAOC3 | |
| SCHEMBL20649045 | 0.89 | CSNK2A1 (0.37) | CSNK2A1CDK2GCKMAOBAOC3 | |
| SCHEMBL20649331 | 0.88 | DCPS (0.35) | ACKR3DCPSCSNK2A1CDK2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |