SCHEMBL20650296

SCHEMBL20650296

Cc1cccc2c1oc1c(N(I)c3ccc(C#N)cc3)cccc12

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP2A6 P11509 1/20 0.32
IDO1 P14902 1/20 0.32
TNKS O95271 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.31
C1R P00736 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650765 0.85 KDM4E (0.33) ALDH1A1TNKSKDM4EGAAMAPT
SCHEMBL21019985 0.85 ABCG2 (0.39) MCL1ALDH1A1CYP2A6TNKSABCG2
SCHEMBL20650355 0.84 AR (0.34) TNKS
SCHEMBL20650451 0.84 KIF11 (0.31)
SCHEMBL20650767 0.84 TNKS (0.32) TNKS
SCHEMBL20650254 0.84 CYP2A6 (0.33) CYP2A6TNKSC1R
SCHEMBL20650419 0.83 MCL1 (0.40) MCL1ALDH1A1CYP2A6
SCHEMBL20650244 0.83 TNKS (0.40) ALDH1A1TNKSABCG2C1RKDM4E
SCHEMBL20650300 0.82 MCL1 (0.34) MCL1
SCHEMBL20650298 0.81 MCL1 (0.33) MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed