Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20650319 | 0.89 | ALOX5 (0.34) | NPC1RAB9APOLBPTGER1ALDH1A1 | |
| SCHEMBL20172804 | 0.85 | POLB (0.36) | NPC1RAB9APOLBPTGER1ALDH1A1 | |
| SCHEMBL20650726 | 0.84 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL20650740 | 0.83 | ALOX5 (0.47) | NPC1RAB9AALDH1A1KEAP1ALOX5 | |
| SCHEMBL20650126 | 0.83 | ESR1 (0.34) | PTGER1ALDH1A1LMNAKDM4EESR1 | |
| SCHEMBL20650481 | 0.82 | ALOX5 (0.30) | ALDH1A1GABRA1GABRB2ALOX5LMNA | |
| SCHEMBL20649838 | 0.81 | TSHR (0.35) | RAB9APOLBALDH1A1KDM4ETSHR | |
| SCHEMBL20650730 | 0.80 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL20650729 | 0.80 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL20650719 | 0.79 | NPC1 (0.33) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428152-B1 | COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-11-03 | — | — | EP | disclosed |
| EP-3428152-A1 | COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | LG Chem, Ltd. (KR) | 2019-01-16 | — | — | EP | disclosed |