Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19870717 | 0.84 | EPAS1 (0.58) | VEGFAEPAS1 | |
| SCHEMBL20650883 | 0.79 | VEGFA (0.43) | VEGFAEPAS1 | |
| SCHEMBL21080634 | 0.73 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL18163795 | 0.73 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL19870708 | 0.73 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL18067967 | 0.73 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL19858582 | 0.73 | EPAS1 (0.52) | VEGFAEPAS1 | |
| SCHEMBL21362857 | 0.71 | EPAS1 (0.50) | VEGFAEPAS1 | |
| SCHEMBL18067969 | 0.70 | VEGFA (0.49) | VEGFAEPAS1 | |
| SCHEMBL19870697 | 0.70 | VEGFA (0.49) | VEGFAEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190015377-A1 | Compositions for Use in Treating Pulmonary Arterial Hypertension | PELOTON THERAPEUTICS, INC. (US) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190015377-A1 | Compositions for Use in Treating Pulmonary Arterial Hypertension | MYLK, TNNI3, PDE2A | VEGFA 34/4885EPAS1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.