Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20650898 | 0.91 | EPAS1 (0.42) | EPAS1VEGFA | |
| SCHEMBL19870711 | 0.84 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL20650883 | 0.82 | VEGFA (0.43) | EPAS1VEGFA | |
| SCHEMBL19870718 | 0.76 | EPAS1 (0.54) | EPAS1VEGFA | |
| SCHEMBL22473049 | 0.72 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL18048380 | 0.72 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL18048426 | 0.71 | EPAS1 (0.54) | EPAS1VEGFA | |
| SCHEMBL18048424 | 0.71 | EPAS1 (0.54) | EPAS1VEGFA | |
| SCHEMBL18049333 | 0.70 | EPAS1 (0.53) | EPAS1VEGFA | |
| SCHEMBL19870722 | 0.70 | EPAS1 (0.53) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190015377-A1 | Compositions for Use in Treating Pulmonary Arterial Hypertension | PELOTON THERAPEUTICS, INC. (US) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190015377-A1 | Compositions for Use in Treating Pulmonary Arterial Hypertension | MYLK, TNNI3, PDE2A | EPAS1 450/4885VEGFA 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.