Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065761 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL5318561 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2065965 | 0.80 | POLB (0.49) | ALDH1A1NPC1RAB9ALTA4H | |
| SCHEMBL2065220 | 0.80 | NPC1 (0.50) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2066372 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2065107 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL6767967 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2065499 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL28931504 | 0.71 | PTGDR2 (0.49) | ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL2065108 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | ALDH1A1 2660/4885HTT 2091/4885SMN1; SMN2 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.