Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184870 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL10216057 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL28669112 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL5958762 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL23005842 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL33608 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL3291266 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL12352871 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL23029423 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL9383261 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1CYP3A4ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |