SCHEMBL33608

SCHEMBL33608

Cc1ccc(N)c(C(C)(O)O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.63
ALOX15 P16050 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 1/20 0.45
CA1 P00915 1/20 0.39
PGR P06401 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
TSHR P16473 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 2/20 0.37
PKM P14618 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3291266 0.87 SMN1; SMN2 (0.63) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL9769170 0.86 SMN1; SMN2 (0.50) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL5535338 0.85 SMN1; SMN2 (0.49) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL28669112 0.82 SMN1; SMN2 (0.57) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL10216057 0.82 SMN1; SMN2 (0.57) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL20528330 0.80 SMN1; SMN2 (0.56) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL23005842 0.78 SMN1; SMN2 (0.53) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL20651276 0.78 SMN1; SMN2 (0.63) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL12352871 0.78 SMN1; SMN2 (1.00) SMN1; SMN2ALOX15TDP1CYP3A4TP53
SCHEMBL5147469 0.78 SMN1; SMN2 (0.58) SMN1; SMN2ALOX15TDP1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119487145-A Toughening adhesives based on (meth) acrylic esters 汉高股份有限及两合公司 2025-02-18 CN claimed
CN-117883290-A Low-oxygen polymerization-inhibition adhesive for dentistry 山东沪鸽口腔材料股份有限公司 2024-04-16 CN claimed
CN-117064765-B Dental adhesive restorative material composition and application thereof 长春新斯达科技有限公司 2023-12-29 CN claimed
CN-117064765-A Dental adhesive restorative material composition and application thereof 长春新斯达科技有限公司 2023-11-17 CN claimed
CN-116874780-A Water-soluble PAI resin and preparation method and application thereof 开封夸克新材料有限公司 2023-10-13 CN claimed
CN-115672200-A Tubular reactor for preparing hydroxypivalaldehyde and application thereof 万华化学集团股份有限公司 2023-02-03 CN claimed
WO-2022268545-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
WO-2022268543-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
WO-2022268544-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
WO-2022268541-A1 MATERIAL SYSTEM FOR 3D PRINTING EVONIK OPERATIONS GMBH (DE) 2022-12-29 WO claimed
EP-0988851-A2 Transparent cement for a temporary dental prosthesis or appliance and method of use Kerr Corporation (US) 2000-03-29 EP claimed
US-5977199-A Composition, delivery system therefor, and method for making temporary crowns and bridges THE KERR CORPORATION (US) 1999-11-02 US claimed
WO-1999040884-B1 COMPOSITION FOR MAKING TEMPORARY CROWNS AND BRIDGES KERR CORP (US) 1999-10-21 WO claimed
WO-1999040884-A1 COMPOSITION FOR MAKING TEMPORARY CROWNS AND BRIDGES KERR CORPORATION (US) 1999-08-19 WO claimed
WO-1999029273-A1 POLYMERIC COMPOSITION FOR SEALING AND SHIELDING ANIMAL SKIN BIOPOLYMER SOLUTIONS, INC. (US) 1999-06-17 WO claimed
US-5650138-A ACTIVATOR FOR CURING A GEL COMPRISING A SOLVENT, A POLYMERIZATION INITIATOR AND A VISCOSITY MODIFIER RESLER RENEE (US) 1997-07-22 US claimed
US-5554665-A PHOTO OR THERMAL ACRYLIC POLYMERIZATION DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1996-09-10 US claimed
US-5444104-A Dental restorative material based on a polycarbonate dimethacrylate JENERIC/PENTRON, INC. (US) 1995-08-22 US claimed
EP-0630641-A1 Method and dispenser for making dental products DENTSPLY INTERNATIONAL, INC. (US) 1994-12-28 EP claimed
US-5276068-A Dimethacrylate compounds containing carbonate groups, adhesives, restoration material JENERIC/PENTRON, INC. (US) 1994-01-04 US claimed