Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014574 | 0.85 | IDO1 (0.43) | IDO1NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL20406934 | 0.83 | NPC1 (0.44) | IDO1NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL12545483 | 0.72 | ALDH1A1 (0.36) | IDO1NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL17073557 | 0.71 | GAA (0.38) | IDO1NPC1RAB9AALDH1A1GSK3B | |
| SCHEMBL21583302 | 0.69 | KDM4E (0.32) | NPC1RAB9AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL17014585 | 0.69 | ALDH1A1 (0.31) | ALDH1A1CYP3A4CYP1A2ALOX15HIF1A | |
| SCHEMBL19929039 | 0.69 | IDO1 (0.31) | IDO1 | |
| SCHEMBL21419580 | 0.67 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP1A2ALOX15HIF1A | |
| SCHEMBL22814613 | 0.67 | PDK2 (0.34) | IDO1 | |
| SCHEMBL12545175 | 0.67 | ALDH1A1 (0.32) | ALDH1A1CYP3A4CYP1A2ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2924020-B1 | FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-01-16 | — | — | EP | disclosed |