Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640202 | 1.00 | OPRM1 (0.85) | OPRM1OPRL1 | |
| SCHEMBL20653754 | 1.00 | OPRM1 (0.85) | OPRM1OPRL1 | |
| SCHEMBL19094091 | 0.92 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19104819 | 0.92 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL29460866 | 0.92 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19094089 | 0.92 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL20389064 | 0.92 | OPRM1 (0.81) | OPRM1OPRL1 | |
| SCHEMBL20640201 | 0.87 | OPRM1 (0.84) | OPRM1OPRL1 | |
| SCHEMBL20647621 | 0.87 | OPRM1 (0.84) | OPRM1OPRL1 | |
| SCHEMBL20647605 | 0.87 | OPRM1 (0.84) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652157-B1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |
| WO-2019012037-A1 | 1,3-DIAZA-SPIRO-[3.4]-OCTANE DERIVATIVES | Grünenthal GmbH (DE) | 2019-01-17 | — | — | WO | disclosed |