Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.44 |
| ▸ | PPARA | Q07869 | 15/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2902922 | 0.91 | PPARD (0.47) | PPARDPPARAPPARGMCL1 | |
| SCHEMBL681341 | 0.85 | PPARD (0.44) | PPARDPPARAPPARGMCL1TP53 | |
| SCHEMBL4808451 | 0.81 | PPARA (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4804485 | 0.78 | PPARA (0.48) | PPARDPPARAPPARG | |
| SCHEMBL4808683 | 0.78 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL5999249 | 0.77 | PPARD (0.42) | PPARDPPARAPPARGTP53 | |
| SCHEMBL4851159 | 0.77 | PPARD (0.51) | PPARDPPARAPPARGMCL1 | |
| SCHEMBL14411904 | 0.76 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL2403715 | 0.76 | PPARA (0.57) | PPARDPPARAPPARG | |
| SCHEMBL4809754 | 0.75 | PPARD (0.59) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964575-B1 | PHARMACEUTICAL COMPRISING PPAR AGONIST | SENJU PHARMA CO (JP) | 2015-09-23 | — | — | EP | disclosed |
| US-9096538-B2 | Pharmaceutical comprising PPAR agonist | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| WO-2013134626-A1 | PREVENTION AND TREATMENT OF RESPIRATORY INFECTION WITH PEROXISOME PROLIFERATOR ACTIVATOR RECEPTOR DELTA AGONIST | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-09-12 | — | — | WO | disclosed |
| US-20120220612-A1 | PHARMACEUTICAL COMPRISING PPAR AGONIST | NAKAMURA YOSHIKUNI (JP) | 2012-08-30 | — | — | US | disclosed |
| US-8148389-B2 | Pharmaceutical comprising PPAR agonist | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20090306111-A1 | Pharmaceutical Comprising PPAR Agonist | SENJU PHARMACEUTICAL CO., LTD (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-1964575-A1 | PHARMACEUTICAL COMPRISING PPAR AGONIST | Senju Pharmaceutical Co., Ltd. (JP) | 2008-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306111-A1 | Pharmaceutical Comprising PPAR Agonist | PPARD, PPARA, PPARG | PPARD 1/4885PPARA 2/4885PPARG 3/4885 |
| US-20120220612-A1 | PHARMACEUTICAL COMPRISING PPAR AGONIST | PPARD, PPARA, PPARG | PPARD 1/4885PPARA 2/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.