Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.57 |
| ▸ | PPARD | Q03181 | 17/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808451 | 0.93 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL4810762 | 0.92 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL4808137 | 0.91 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL4813025 | 0.89 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL4815199 | 0.88 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL4850099 | 0.87 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL4804485 | 0.87 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL4806547 | 0.87 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL4812232 | 0.87 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL4809628 | 0.86 | PPARA (0.47) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224264-A1 | MEDICAMENTS | BROWN KATHLEEN KEATING | 2011-09-15 | — | — | US | disclosed |
| US-20110224264-A1 | MEDICAMENTS | BROWN KATHLEEN KEATING | 2011-09-15 | — | — | US | disclosed |
| US-20110224264-A1 | MEDICAMENTS | BROWN KATHLEEN KEATING | 2011-09-15 | — | — | US | disclosed |
| US-20100280080-A1 | Medicaments | BROWN KATHLEEN KEATING | 2010-11-04 | — | — | US | disclosed |
| US-20100280080-A1 | Medicaments | BROWN KATHLEEN KEATING | 2010-11-04 | — | — | US | disclosed |
| US-7767682-B2 | Medicaments | GLAXOSMITHKLINE LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767682-B2 | Medicaments | GLAXOSMITHKLINE LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767682-B2 | Medicaments | GLAXOSMITHKLINE LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-20080113996-A1 | Medicaments | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080113996-A1 | Medicaments | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-15 | — | — | US | disclosed |
| EP-1853258-A4 | MEDICAMENTS | SMITHKLINE BEECHAM CORP (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1853258-A2 | MEDICAMENTS | SmithKline Beecham Corporation (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006096398-A2 | MEDICAMENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224264-A1 | MEDICAMENTS | GLS, PKD1, ATP6V1B1 | PPARA 4/4885PPARD 7/4885PPARG 6/4885 |
| US-20080113996-A1 | Medicaments | GLS, PKD1, ATP6V1B1 | PPARA 4/4885PPARD 7/4885PPARG 6/4885 |
| US-20100280080-A1 | Medicaments | GLS, PKD1, ATP6V1B1 | PPARA 4/4885PPARD 7/4885PPARG 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.