Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.95 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | HPGD | P15428 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorophenothane SCHEMBL7181 | 0.97 | TSHR (1.00) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL2065589 | 0.97 | TSHR (1.00) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL3798614 | 0.95 | TSHR (0.95) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL9765829 | 0.95 | TSHR (0.95) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL7765752 | 0.95 | TSHR (0.95) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL10725072 | 0.95 | TSHR (0.95) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL8508193 | 0.92 | TSHR (0.90) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL28353116 | 0.90 | TSHR (0.86) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL11570317 | 0.90 | TSHR (0.86) | TSHRMAPK1TDP1HIF1ALMNA | |
| Chlorophenothane SCHEMBL30308710 | 0.88 | TSHR (0.82) | TSHRMAPK1TDP1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8776026-B2 | System and method for in-vivo multi-path analysis of binary software | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2014-07-08 | — | — | US | disclosed |
| US-20120084759-A1 | SYSTEM AND METHOD FOR IN-VIVO MULTI-PATH ANALYSIS OF BINARY SOFTWARE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2012-04-05 | — | — | US | disclosed |