Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 11/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656034 | 0.88 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL20656211 | 0.80 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL20656226 | 0.78 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL20652792 | 0.77 | PDE5A (0.43) | P2RX3ADORA3 | |
| SCHEMBL20652791 | 0.75 | P2RX3 (0.46) | P2RX3ADORA3 | |
| SCHEMBL20656201 | 0.73 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL24095610 | 0.71 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL20653077 | 0.69 | P2RX3 (0.47) | P2RX3 | |
| SCHEMBL22105571 | 0.68 | PDE5A (0.51) | P2RX3ADORA3 | |
| SCHEMBL20652775 | 0.68 | P2RX3 (0.45) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |