Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643450 | 0.84 | RET (0.46) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL20656240 | 0.75 | DPP4 (0.35) | KMT2A | |
| SCHEMBL16868840 | 0.75 | RET (0.46) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL16868841 | 0.72 | RET (0.41) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL23338509 | 0.72 | KMT2A (0.39) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL20656243 | 0.72 | SCN9A (0.40) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL20646738 | 0.72 | RET (0.51) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL15167200 | 0.71 | RET (0.40) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL15167199 | 0.71 | RET (0.40) | RETKDRKMT2ARAB9AALDH1A1 | |
| SCHEMBL13450908 | 0.70 | RET (0.43) | RETKDRKMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011708-A1 | PROCESS FOR MAKING HIGHER ETHYLENE AMINES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-01-17 | — | — | WO | disclosed |