Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780 | 0.90 | — | — | |
| SCHEMBL22030393 | 0.89 | ALDH1A1 (0.42) | SCN9AALDH1A1KDM4EPOLBMAPT | |
| Ammonia Solution, Strong SCHEMBL1579773 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBMAPTCYP2C9 | |
| SCHEMBL22030391 | 0.84 | ALDH1A1 (0.41) | SCN9AALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL14426096 | 0.82 | ALDH1A1 (0.42) | SCN9AALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL471725 | 0.82 | ALOX15 (0.41) | POLBCYP2C9CYP2C19CYP2D6KMT2A | |
| SCHEMBL13236669 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBMAPTCYP2C9 | |
| SCHEMBL23338509 | 0.81 | KMT2A (0.39) | SCN9AALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL8406068 | 0.81 | ALOX15 (0.48) | ALDH1A1KDM4EPOLBMAPTCYP2C9 | |
| SCHEMBL21923029 | 0.80 | ALDH1A1 (0.44) | SCN9AALDH1A1KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339116-B2 | Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2022-05-24 | — | — | US | disclosed |
| US-11214549-B2 | Process for making higher ethylene amines | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2022-01-04 | — | — | US | disclosed |
| EP-3665154-B1 | REACTIVE SEPARATION PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES | NOURYON CHEMICALS INT BV (NL) | 2021-05-12 | — | — | EP | disclosed |
| US-20200361851-A1 | REACTIVE SEPARATION PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-11-19 | — | — | US | disclosed |
| WO-2020161145-A1 | COMPOUNDS WITH AT LEAST ONE CYCLIC UREA MOIETY AND THEIR USE IN CORROSION PREVENTION | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-08-13 | — | — | WO | disclosed |
| US-20200165207-A1 | PROCESS FOR MAKING HIGHER ETHYLENE AMINES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-05-28 | — | — | US | disclosed |
| WO-2019011708-A1 | PROCESS FOR MAKING HIGHER ETHYLENE AMINES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339116-B2 | Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines | UTP20, CGAS, UMPS | SCN9A 3153/4885ALDH1A1 2104/4885KDM4E 2774/4885 |
| US-11214549-B2 | Process for making higher ethylene amines | HRH4, HRH3, HRH1 | SCN9A 2907/4885ALDH1A1 1957/4885KDM4E 444/4885 |
| US-20200361851-A1 | REACTIVE SEPARATION PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES | UTP20, CGAS, UMPS | SCN9A 3153/4885ALDH1A1 2104/4885KDM4E 2774/4885 |
| US-20200165207-A1 | PROCESS FOR MAKING HIGHER ETHYLENE AMINES | HRH4, HRH3, HRH1 | SCN9A 2998/4885ALDH1A1 1953/4885KDM4E 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.