SCHEMBL20656259

SCHEMBL20656259

CC(F)(F)CC(O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL757240 0.78
SCHEMBL8874121 0.78
SCHEMBL757239 0.78
SCHEMBL4135528 0.78
SCHEMBL1132105 0.76
SCHEMBL5138836 0.76
Hydrochloric Acid SCHEMBL1825390 0.76 CETP (0.43)
SCHEMBL29512386 0.76 GABRR1 (0.36)
SCHEMBL21199073 0.72 CETP (0.40)
SCHEMBL1132763 0.72 GABRR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869374-B 2-oxo-1, 3-oxazolidinyl imidazothiadiazole derivatives UCB生物制药有限责任公司 2022-08-30 CN disclosed
CN-110869375-B 2-oxo-1-imidazolidinylimidazothiadiazole derivatives UCB生物制药有限责任公司 2022-08-30 CN disclosed
US-11155565-B2 2-oxo-1,3-oxazolidinyl imidazothiadiazole derivatives UCB Biopharma SRL 2021-10-26 US disclosed
EP-3652183-B1 2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB Biopharma SRL (BE) 2021-09-08 EP disclosed
EP-3652182-B1 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB Biopharma SRL (BE) 2021-09-08 EP disclosed
US-20200231599-A1 2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB BIOPHARMA SPRL (BE) 2020-07-23 US disclosed
WO-2019011770-A1 2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB BIOPHARMA SPRL (BE) 2019-01-17 WO disclosed