⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135528 | 1.00 | — | — | |
| SCHEMBL2163787 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL29512386 | 0.80 | GABRR1 (0.36) | — | |
| SCHEMBL5138836 | 0.80 | — | — | |
| SCHEMBL1132105 | 0.80 | — | — | |
| SCHEMBL20656259 | 0.78 | — | — | |
| SCHEMBL28117175 | 0.78 | GABBR2 (0.32) | — | |
| SCHEMBL1132763 | 0.76 | GABRR1 (0.33) | — | |
| SCHEMBL502445 | 0.76 | GABRR1 (0.33) | — | |
| SCHEMBL13071622 | 0.75 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212148-A1 | THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-5670652-A | REACTION OF NEOPENTYLGLYCINOL WITH CHLOROFORMIC ACID TO FORM ALKYLOXAZOLIDINONE | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0692478-A1 | Process for the preparation of optically active 4 substituted (S)-2-oxazolidinone, optically active (S)-aminoalcohols and utilization of there compounds | Degussa Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0692538-A2 | Process for producing optically active L-amino acids, novel optically active L-aminoacids with bulky side-chains and their use | Degussa Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |