Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexanoate SCHEMBL3867 | 1.00 | — | — | |
| Adipic Acid SCHEMBL31546519 | 1.00 | AKR1B1 (1.00) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL160301 | 1.00 | AKR1B1 (1.00) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL1330703 | 1.00 | — | — | |
| Hexanoate SCHEMBL1332504 | 1.00 | — | — | |
| Hexanoate SCHEMBL4619316 | 1.00 | AKR1B1 (1.00) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL28202055 | 1.00 | AKR1B1 (1.00) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL27362881 | 1.00 | AKR1B1 (1.00) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL29695652 | 1.00 | — | — | |
| Dodecanoate SCHEMBL25293218 | 0.97 | GPR84 (1.00) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253577-A | Method for preparing modified epoxy acrylate | 黎明化工研究设计院有限责任公司 | 2020-06-09 | — | — | CN | claimed |
| US-20250091260-A1 | METHOD FOR MANUFACTURING RESIN SHEET BY USING 3D PRINTER, AND POLISHING PAD HAVING POLISHING LAYER OBTAINED THEREBY | KURARAY CO., LTD. (JP) | 2025-03-20 | — | — | US | disclosed |
| US-20240383097-A1 | POLISHING PAD | KURARAY CO., LTD. (JP) | 2024-11-21 | — | — | US | disclosed |
| US-20240375239-A1 | POLISHING PAD | KURARAY CO., LTD. (JP) | 2024-11-14 | — | — | US | disclosed |
| WO-2023228835-A1 | HOT-MELT ADHESIVE SHEET | 日東シンコー株式会社 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023214494-A1 | MOISTURE-CURABLE URETHANE HOT MELT RESIN COMPOSITION, MULTILAYER BODY AND SYNTHETIC ARTIFICIAL LEATHER | 大日精化工業株式会社 | 2023-11-09 | — | — | WO | disclosed |
| WO-2023145933-A1 | METHOD FOR MANUFACTURING RESIN SHEET BY USING 3D PRINTER, AND POLISHING PAD HAVING POLISHING LAYER OBTAINED THEREBY | 株式会社クラレ | 2023-08-03 | — | — | WO | disclosed |
| WO-2023048265-A1 | POLISHING PAD | 株式会社クラレ | 2023-03-30 | — | — | WO | disclosed |
| WO-2023048266-A1 | POLISHING PAD | 株式会社クラレ | 2023-03-30 | — | — | WO | disclosed |
| EP-4072317-A1 | POUCHED PRODUCTS WITH HEAT SEALABLE BINDER | Nicoventures Trading Limited (GB) | 2022-10-19 | — | — | EP | disclosed |
| EP-0189945-B2 | Aqueous polyurethane-polyolefin compositions | WITCO CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5310827-A | Polyamide copolymers | KURARAY CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5233015-A | Polyhexamethylene adipate having controlled viscosity, low melting, toughness, resilience, lamination adhesives | BOSTIK, INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5115048-A | Coating a mold before molding a polyurethane of a diisocyanate and a polycarbonate polyol and a hardener | NISSAN MOTOR CO., LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| US-5093437-A | Polyamideester Block Polymers From Telechelic Polyesters | KURARAY CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0448079-A2 | High-molecular weight polyhexamethylene adipate | BOSTIK LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| EP-0332339-A2 | Thermoplastic polymer composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4644030-A | FORMING POLYURETHANE PREPOLYMER IN INERT POLYMERIZABLE ETHYLENTICALLY UNSATURATED MONOMER, DISPERSING IN WATER, CHAIN EXTENDING, AND POLYMERIZING | WITCO CORPORATION (US) | 1987-02-17 | — | — | US | disclosed |
| US-4400498-A | CHAIN EXTENSION OF POLYETHER- AND -ESTERURETHANE COPOLYMERS WITH A TRIOL; ADHESIVES | SONY CORPORATION (JP) | 1983-08-23 | — | — | US | disclosed |
| US-4368238-A | THERMOPLASTIC POLYURETHANE AS BINDER | SONY CORPORATION (JP) | 1983-01-11 | — | — | US | disclosed |