Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656732 | 0.85 | BRD4 (0.47) | MTNR1AMTNR1BHSD17B10TP53BRD4 | |
| SCHEMBL121590 | 0.82 | BRD4 (0.41) | MTNR1AMTNR1BHSD17B10TP53BRD4 | |
| SCHEMBL30434777 | 0.82 | BRD4 (0.41) | MTNR1AMTNR1BHSD17B10TP53BRD4 | |
| SCHEMBL30434539 | 0.78 | BRD4 (0.61) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL122813 | 0.78 | BRD4 (0.61) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL121574 | 0.67 | BRD4 (0.51) | MTNR1AMTNR1BHSD17B10TP53BRD4 | |
| SCHEMBL30435329 | 0.67 | BRD4 (0.51) | MTNR1AMTNR1BHSD17B10TP53BRD4 | |
| SCHEMBL19194515 | 0.66 | EZH2 (0.53) | MTNR1AMTNR1BHSD17B10TP53EZH2 | |
| SCHEMBL146515 | 0.64 | GUSB (0.50) | BRD4CYP1A1CYP1A2CYP1B1KDM4E | |
| SCHEMBL30434560 | 0.64 | GUSB (0.50) | BRD4CYP1A1CYP1A2CYP1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431086-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | Resverlogix Corp. (CA) | 2019-01-23 | — | — | EP | disclosed |