Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | F13A1 | P00488 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515109 | 0.99 | TTR (0.40) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9319479 | 0.94 | TTR (0.41) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6248837 | 0.93 | TTR (0.40) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29586703 | 0.91 | TTR (0.43) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31668182 | 0.91 | TTR (0.41) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9319210 | 0.91 | TTR (0.41) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6053862 | 0.88 | CYP3A4 (0.43) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL87887 | 0.74 | HCAR2 (0.43) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8314107 | 0.74 | HSP90AA1 (0.39) | TDP1FFAR4MAPTALDH1A1 | |
| SCHEMBL1122760 | 0.74 | HCAR2 (0.43) | TTRAKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230090172-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHOGS OF MAKING | VirTech Bio, Inc. | 2023-03-23 | — | — | US | disclosed |
| US-20200222510-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHODS OF MAKING | VirTech Bio, Inc. | 2020-07-16 | — | — | US | disclosed |
| EP-3655019-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHODS OF MAKING | Virtech Bio, Inc. (US) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019018403-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHODS OF MAKING | VIRTECH BIO, LLC (US) | 2019-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222510-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHODS OF MAKING | HBG1, HBG2, HBB | TTR 18/4885AKR1C4 3207/4885AKR1C3 3048/4885 |
| US-20230090172-A1 | BLOOD SUBSTITUTES COMPRISING HEMOGLOBIN AND METHOGS OF MAKING | HBG1, HBG2, HBB | TTR 16/4885AKR1C4 3946/4885AKR1C3 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.