SCHEMBL2066262

SCHEMBL2066262

CCSc1ccc2nc(C)c(S(=O)(=O)Cl)n2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 9/20 0.43
KDM4E B2RXH2 8/20 0.43
ALDH1A1 P00352 6/20 0.43
HSD17B10 Q99714 6/20 0.43
ALOX15 P16050 3/20 0.43
HTT P42858 3/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
RXFP1 Q9HBX9 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
PDE10A Q9Y233 1/20 0.39
CYP1A2 P05177 1/20 0.34
HTR6 P50406 3/20 0.33
TP53 P04637 1/20 0.33
MAOB P27338 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
NOTUM Q6P988 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066633 0.86 HPGD (0.43) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL2066260 0.77 PDE10A (0.38) KDM4EHSD17B10PDE10A
SCHEMBL2066089 0.77 TNF (0.43) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL3349145 0.75 HPGD (0.40) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL2065997 0.73
SCHEMBL3344893 0.72 KDM4E (0.40) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL3346096 0.70 MEN1 (0.38) HPGDKDM4EALDH1A1HSD17B10HTT
SCHEMBL2066936 0.69 TNF (0.57) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL2066681 0.68 PDE4A (0.40) HTT
SCHEMBL2065620 0.66 DYRK1A (0.46) HPGDKDM4EALDH1A1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 HPGD 4787/4885KDM4E 3606/4885ALDH1A1 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.