SCHEMBL2066313

SCHEMBL2066313

CCCc1ccc2nc(C#N)c(S(=O)(=O)Cl)n2n1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.40
CTSK P43235 4/20 0.33
CTSS P25774 3/20 0.33
CYP19A1 P11511 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066672 0.88 PDE10A (0.40) PDE10ACTSKCTSSKDM4EHSD17B10
SCHEMBL2066260 0.82 PDE10A (0.38) PDE10AKDM4EHSD17B10
SCHEMBL2066602 0.82 PDE10A (0.32) PDE10A
SCHEMBL2066696 0.82 PDE10A (0.37) PDE10A
SCHEMBL2065623 0.81 PDE10A (0.31) PDE10A
SCHEMBL2066641 0.81 PDE10A (0.30) PDE10A
SCHEMBL2065990 0.81 JAK1 (0.32) PDE10AKDM4E
SCHEMBL2066142 0.80
SCHEMBL2067045 0.79 PDE10A (0.31) PDE10A
SCHEMBL2067668 0.77 PDE10A (0.33) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE10A 3486/4885CTSK 3030/4885CTSS 2531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.