Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467627 | 0.75 | TSHR (0.33) | METAP1 | |
| SCHEMBL19497252 | 0.73 | TSHR (0.32) | METAP1 | |
| SCHEMBL364354 | 0.72 | — | — | |
| SCHEMBL21118226 | 0.72 | METAP1 (0.43) | METAP1 | |
| SCHEMBL22810400 | 0.70 | TSHR (0.39) | — | |
| SCHEMBL11304728 | 0.69 | — | — | |
| SCHEMBL22085515 | 0.69 | — | — | |
| SCHEMBL22686495 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL2066948 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL5798207 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |