Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.66 |
| ▸ | PGR | P06401 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | SHBG | P04278 | 2/20 | 0.66 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066330 | 1.00 | ESR1 (0.66) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL5713538 | 1.00 | ESR1 (0.66) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL9019408 | 1.00 | ESR1 (0.66) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL11685553 | 0.90 | ESR1 (0.67) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL11687882 | 0.90 | ESR1 (0.67) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL11794680 | 0.87 | ESR1 (0.68) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL8781391 | 0.83 | ESR1 (0.51) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL5155107 | 0.83 | ESR1 (0.55) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL1657388 | 0.82 | STS (0.47) | ESR1ESR2NR3C1PGRCYP3A4 | |
| SCHEMBL6259610 | 0.81 | ESR1 (0.45) | ESR1ESR2NR3C1PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8147811-B1 | Use of hyaluronic acid derivatives in pharmaceutical preparations and biomaterials for the prevention and treatment of cutaneous scars | FIDIA FARMACEUTICI S.P.A. (IT) | 2012-04-03 | — | — | US | disclosed |
| EP-1712228-A2 | Hyaluronic acid derivatives for the prevention and treatment of cutaneous scars | FIDIA FARMACEUTICI S.p.A. (IT) | 2006-10-18 | — | — | EP | disclosed |
| EP-1196179-B8 | HYALURONIC ACID ESTERS FOR THE TREATMENT OF NORMOTROPHIC SCARRING OF THE SKIN | FIDIA FARMACEUTICI (IT) | 2006-10-11 | — | — | EP | disclosed |
| EP-1196179-B1 | HYALURONIC ACID ESTERS FOR THE TREATMENT OF NORMOTROPHIC SCARRING OF THE SKIN | FIDIA FARMACEUTICI (IT) | 2006-08-16 | — | — | EP | disclosed |
| EP-1142595-B1 | Biomaterials for bone replacement | FIDIA FARMACEUTICI (IT) | 2005-11-23 | — | — | EP | disclosed |
| EP-0954323-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A MIXTURE OF AUTOCROSS-LINKED HYALURONIC ACID AND NONAUTOCROSS-LINKED HYALURONIC ACID AND THEIR USE FOR THE TREATMENT OF ARTHROPATHIES | FIDIA SPA (IT) | 2004-01-07 | — | — | EP | disclosed |
| US-6533820-B2 | Paste comprising a bonding solution of a 50% benzyl ester of hyaluronic acid and granules of hydroxyapatite | FIDIA S.P.A. (IT) | 2003-03-18 | — | — | US | disclosed |
| EP-0637254-B1 | BIOMATERIALS FOR BONE REPLACEMENTS | FIDIA SPA (IT) | 2002-10-16 | — | — | EP | disclosed |
| EP-1196179-A2 | HYALURONIC ACID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF CUTANEOUS SCARS | FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) | 2002-04-17 | — | — | EP | disclosed |
| US-20010053938-A1 | BIOMATERIALS FOR BONE REPLACEMENTS | RAYMOND C. STEWART | 2001-12-20 | — | — | US | disclosed |
| WO-1993020858-A1 | BIOMATERIALS FOR BONE REPLACEMENTS | FIDIA S.P.A (IT) | 1993-10-28 | — | — | WO | disclosed |
| WO-1993014129-A1 | ESTERS OF PECTIC AND PECTINIC ACID | M.U.R.S.T. (IT) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993011805-A1 | COMPOSITE MEMBRANES FOR THE GUIDED REGENERATION OF TISSUES | M.U.R.S.T. (IT) | 1993-06-24 | — | — | WO | disclosed |
| WO-1993011803-A1 | NON-WOVEN FABRIC MATERIAL COMPRISING HYALURONIC ACID DERIVATIVES | M.U.R.S.T. (IT) | 1993-06-24 | — | — | WO | disclosed |
| EP-0518710-A1 | Gellan esters | FIDIA S.p.A. (IT) | 1992-12-16 | — | — | EP | disclosed |
| US-5147861-A | Esters of alginic acid | FIDIA S.P.A. (IT) | 1992-09-15 | — | — | US | disclosed |
| EP-0342557-A1 | New polysaccharide esters | FIDIA S.p.A. (IT) | 1989-11-23 | — | — | EP | disclosed |
| EP-0341745-A1 | Crosslinked carboxy polysaccharides | FIDIA S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| US-4851521-A | Esters of hyaluronic acid | FIDIA, S.P.A. (IT) | 1989-07-25 | — | — | US | disclosed |
| EP-0251905-A2 | Esters of alginic acid | FIDIA S.p.A. (IT) | 1988-01-07 | — | — | EP | disclosed |