SCHEMBL9019408

SCHEMBL9019408

C#C[C@]1(O)CC[C@H]2[C@@H]3C(C)Cc4cc(O)ccc4[C@H]3CC[C@@]21C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.66
ESR2 Q92731 4/20 0.66
NR3C1 P04150 4/20 0.66
PGR P06401 4/20 0.66
CYP3A4 P08684 3/20 0.66
SLC6A4 P31645 3/20 0.66
SLC6A3 Q01959 3/20 0.66
ABCB11 O95342 2/20 0.66
ADORA3 P0DMS8 2/20 0.66
OPRK1 P41145 2/20 0.66
PDE4D Q08499 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
SLC6A2 P23975 2/20 0.66
SHBG P04278 2/20 0.66
SLC22A2 O15244 1/20 0.66
NR1I2 O75469 1/20 0.66
HTR1A P08908 1/20 0.66
AR P10275 1/20 0.66
ADRB3 P13945 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066330 1.00 ESR1 (0.66) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL2066331 1.00 ESR1 (0.66) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL5713538 1.00 ESR1 (0.66) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL11685553 0.90 ESR1 (0.67) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL11687882 0.90 ESR1 (0.67) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL11794680 0.87 ESR1 (0.68) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL8781391 0.83 ESR1 (0.51) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL5155107 0.83 ESR1 (0.55) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL1657388 0.82 STS (0.47) ESR1ESR2NR3C1PGRCYP3A4
SCHEMBL6259610 0.81 ESR1 (0.45) ESR1ESR2NR3C1PGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0518710-B1 Gellan esters FIDIA SPA (IT) 1996-05-22 EP disclosed
US-5332809-A Partial esters of gellan FIDIA S.P.A. (IT) 1994-07-26 US disclosed
EP-0518710-A1 Gellan esters FIDIA S.p.A. (IT) 1992-12-16 EP disclosed