Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109500 | 0.86 | GGPS1 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17225210 | 0.85 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL22109281 | 0.84 | GGPS1 (0.46) | CHRM2GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL18685899 | 0.84 | KDM5A (0.32) | — | |
| SCHEMBL11885538 | 0.81 | GGPS1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13649903 | 0.80 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18799382 | 0.80 | TSHR (0.41) | TSHRTDP1 | |
| SCHEMBL20879980 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL19706307 | 0.79 | GGPS1 (0.48) | CHRM2GGPS1FDPSAGTR1OPRM1 | |
| SCHEMBL23695719 | 0.78 | SIGMAR1 (0.42) | CHRM2GGPS1FDPSAGTR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230410-B1 | AROMATICS HYDROGENATION CATALYST, ITS PREPARATION AND USE THEREOF | EXXONMOBIL RES & ENG CO (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3229952-B1 | ORGANOSILICA MATERIALS | EXXONMOBIL RES & ENG CO (US) | 2019-01-23 | — | — | EP | disclosed |